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SRX1881058: GSM2218836: SMAD2/3, MCF10A MII, TGFβ 16h_ChIP; Homo sapiens; ChIP-Seq
1 ILLUMINA (Illumina HiSeq 2000) run: 39.8M spots, 1.4G bases, 710.8Mb downloads

Submitted by: NCBI (GEO)
Study: SMAD2/3 binding pattern in a breast epithelial cell line, MCF10A MII [ChIP-seq]
show Abstracthide Abstract
We report that SMAD2/3 are redirected to novel binding sites on the genome after prolonged TGFß stimulation. Overall design: SMAD2/3 ChIP-seq analyses were performed in MCF10A MII cells at 2 different time points after TGFß treatment.
Sample: SMAD2/3, MCF10A MII, TGFβ 16h_ChIP
SAMN05296862 • SRS1527769 • All experiments • All runs
Organism: Homo sapiens
Library:
Instrument: Illumina HiSeq 2000
Strategy: ChIP-Seq
Source: GENOMIC
Selection: ChIP
Layout: SINGLE
Construction protocol: Chromatin isolation, sonication and immunoprecipitation using anti-SMAD2/3 antibody (#610843, BD Transduction Laboratories) were performed essentially as described (Isogaya et al., 2014; Morikawa et al., 2016). The library was prepared using NEBNext ChIP-Seq Library Prep Reagent Set for Illumina (New England Biolabs) or KAPA DNA Library Preparation Kits for Illumina (KAPA Biosystems).
Experiment attributes:
GEO Accession: GSM2218836
Links:
Runs: 1 run, 39.8M spots, 1.4G bases, 710.8Mb
Run# of Spots# of BasesSizePublished
SRR372353139,823,7651.4G710.8Mb2017-11-22

ID:
2687767

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